1. Multiple sclerosis plaques involve spinal roots

2. All MS follows a relapsing and exacerbating course

3. Is remyelination in the central nervous system possible?

4. Axons are not damaged in multiple sclerosis

5. MS is more common in northern countries

6. Which of the following is useful for treating MS?

*7. A 32 year old woman developed acute neurologic deficits and contrast enhancing periventricular lesions. A stereotactic biopsy revealed changes shown below.

Immunohistochemistry of this lesion will show:

8. Conduction velocity in the peroneal nerve of a patient with MS and paraparesis is:

9. The risk of MS in the identical twin of a patient with MS is:

10. Which of the following is not seen in old MS lesions?

11. Devic's disease is characterized by involvement of:

12. Which of the following is most commonly affected in MS?

13. A 37 year old man had progressive neurologic deficits including hemiparesis and ataxia for nine months. CSF shows 37 lymphocytes, protein 54, glucose 50, and no oligoclonal bands. The most likely diagnosis is:

14. A 12 year old white male had progressive psychomotor decline for three years and the MRI findings shown below

The CSF shows 15 lymphocytes, glucose 67, protein 43, and normal CSF IgG/albumin ratio. The most likely diagnosis is:

*15. A 37 year old man with AIDS developed ataxia and paralysis. The MRI shows cerebellar and brainstem nonenhancing lesions. The cerebellar biopsy includes mostly normal cerebellar cortex and a small amount of white matter which shows a few mononuclear cells, macrophages and reactive astrocytes. The best use of the material in order to obtain a diagnosis is:

16. Which of the following structures is most commonly affected in MS?

17. A 26 year old woman developed severe dizziness, hoarseness, extension of the neck, and right arm weakness in the course of 8 days. The MRI shows enhancing lesions in the lower brainstem and upper spinal cord. A stereotactic biopsy is shown below.

The most likely diagnosis is:

*18. A 32 year old hemophiliac patient developed neurologic deficits and enhancing cerebral and cerebellar white matter lesions over a period of four months. A stereotactic biopsy of the cerebellum is shown below.

The most likely diagnosis is:

19. The pathology illustrated in this myelin stained section of the pons is likely to occur in all of the following conditions except:

20. Stereotactic brain biopsy of a ring enhancing lesion of the left frontal lobe in a previously healthy 37 year old woman who had neurological symptoms for 2 months. Work up showed no fever, sinusitis or other findings. The most likely diagnosis is:

22. The pathology in a 17 year old male shown below represents: