DIMITRI P. AGAMANOLIS, M. D. Akron Childrens Hospital NorthEastern Ohio Universities College of Medicine Neuropathology
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NEOUCOM M2-NEUROLOGY MODULE-NEUROPATHOLOGY

NEUROPATHOLOGY LECTURE TOPICS AND READING ASSIGNMENTS

April 4, 2008, 12:00 Noon: Perinatal disorders--- podcast (all web pages in this chapter)
April 7, 2008, 10:00 AM: Demyelinating diseases--- podcast (all web pages in this chapter except Central Pontine Myelinolysis)
April 9, 2008, 11:00 AM: Cerebral ischemia and stroke (all web pages in this chapter)
April 9, 2008, 12:00 Noon: CNS Infections (all web pages in this chapter)
April 14, 2008, 9:00 AM: Brain tumors (all web pages in this chapter)
April 14, 2008, 10:00 AM:Peripheral Neuropathy (all web pages in this chapter)
April 14, 2008, 11:00 AM:Myopathology (all web pages in this chapter)
April 16, 2008, 8:00 AM: Degenerative diseases (all web pages in this chapter)
April 16, 2008, 9:00 AM: Traumatic Brain Injury & CJD (all web pages in the TBI chapter and Prion Diseases in CNS Infections)

LABORATORIES
Lab 1 (Cerebral ischemia and stroke, CNC infections, Demyelinative diseases)
Lab 2 (Traumatic brain injury, Brain tumors)
Lab 3 (Perinatal disorders, Degenerative diseases, Neuromuscular pathology)

LEARNING OBJECTIVES

GENERAL INSTRUCTIONS FOR NEUROPATHOLOGY

The Neuropathology component of the Neurology/Geriatrics/Eye Module of the step 3 Curriculum consists of 8 lectures, most of which precede clinical lectures on the same topics.

It would help if, before starting Neuropathology, you refresh your memory on the following items:

1. Basic gross anatomy: the meninges; the lobes of the brain, gross cortical landmarks (the motor and visual cortex, hippocampus, the Sylvian fissure); the visual pathway; the ventricles of the brain and their openings; the basal ganglia and thalamus; the brainstem (midbrain, pons, medulla, aqueduct, cerebral peduncles, substantia nigra, main brainstem nuclei, cranial nerves); the cerebellum; the main cerebral arteries and their territories.

2. Basic histology and reactions, e.g., axons, myelin, gliosis, microglial nodule, macrophages, what "degeneration" means. You will find these in Chapter 1"Neurocytology and basic reactions”. Some of these concepts are also explained at the beginning of each chapter.

Study each topic once well before the lecture. The lectures will not be a repetition of the web site material and will not dwell on details. It will be assumed that you have read the material and you are familiar with it in a general way. The lectures will then focus on basic principles of pathology and how they relate to clinical practice. They will contain mock tests and will be interactive as much as possible.

The labs are exercises that will further solidify your knowledge of basic principles and help you prepare for the exam. See Laboratories for further instructions.

If you follow the above plan, you will not need much further study. You will save yourselves time, and breeze through the course and the exam without anxiety. More important, you will have learned basic clinical neuropathology.